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Chronic lymphocytic leukemia: a disease of activated monoclonal B cells

B-cell type chronic lymphocytic leukemia (CLL) has long been considered a disease of resting lymphocytes. However cell surface and intracellular phenotypes suggest that most CLL cells are activated cells, although only a small subset progresses beyond the G1 stage of the cell cycle. In addition, tra...

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Autores principales: Damle, Rajendra N., Calissano, Carlo, Chiorazzi, Nicholas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921990/
https://ncbi.nlm.nih.gov/pubmed/20620969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2010.02.001
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