In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia

Clonal evolution and outgrowth of cellular variants with additional chromosomal abnormalities are major causes of disease progression in chronic lymphocytic leukemia (CLL). Because new DNA lesions occur during S phase, proliferating cells are at the core of this problem. In this study, we used in vi...

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Detalhes bibliográficos
Main Authors: Calissano, Carlo, Damle, Rajendra N., Hayes, Gregory, Murphy, Elizabeth J., Hellerstein, Marc K., Moreno, Carol, Sison, Cristina, Kaufman, Matthew S., Kolitz, Jonathan E., Allen, Steven L., Rai, Kanti R., Chiorazzi, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925477/
https://ncbi.nlm.nih.gov/pubmed/19789386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-219634
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