In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia

Clonal evolution and outgrowth of cellular variants with additional chromosomal abnormalities are major causes of disease progression in chronic lymphocytic leukemia (CLL). Because new DNA lesions occur during S phase, proliferating cells are at the core of this problem. In this study, we used in vi...

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Hlavní autoři: Calissano, Carlo, Damle, Rajendra N., Hayes, Gregory, Murphy, Elizabeth J., Hellerstein, Marc K., Moreno, Carol, Sison, Cristina, Kaufman, Matthew S., Kolitz, Jonathan E., Allen, Steven L., Rai, Kanti R., Chiorazzi, Nicholas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925477/
https://ncbi.nlm.nih.gov/pubmed/19789386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-219634
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