Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells

The failure of chemotherapeutic regimens to eradicate cancers often results from the outgrowth of minor subclones with more dangerous genomic abnormalities or with self-renewing capacity. To explore such intratumor complexities in B-cell chronic lymphocytic leukemia (CLL), we measured B-cell kinetic...

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Detalhes bibliográficos
Main Authors: Calissano, Carlo, Damle, Rajendra N, Marsilio, Sonia, Yan, Xiao-Jie, Yancopoulos, Sophia, Hayes, Gregory, Emson, Claire, Murphy, Elizabeth J, Hellerstein, Marc K, Sison, Cristina, Kaufman, Matthew S, Kolitz, Jonathan E, Allen, Steven L, Rai, Kanti R, Ivanovic, Ivana, Dozmorov, Igor M, Roa, Sergio, Scharff, Matthew D, Li, Wentian, Chiorazzi, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321822/
https://ncbi.nlm.nih.gov/pubmed/21968788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00360
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