Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin

Many B-cell chronic lymphocytic leukemia (CLL) monoclonal antibodies (mAbs) can be grouped into subsets based on nearly identical stereotyped sequences. Subset 6 CLL mAbs recognize nonmuscle myosin heavy chain IIA (MYHIIA). Herein, we report that during apoptosis, MYHIIA becomes exposed on the cell...

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Detalhes bibliográficos
Main Authors: Chu, Charles C., Catera, Rosa, Zhang, Lu, Didier, Sebastien, Agagnina, Briana M., Damle, Rajendra N., Kaufman, Matthew S., Kolitz, Jonathan E., Allen, Steven L., Rai, Kanti R., Chiorazzi, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869555/
https://ncbi.nlm.nih.gov/pubmed/20110421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-244251
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