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Regulated Proteolysis of Nonmuscle Myosin IIA Stimulates Osteoclast Fusion

The nonmuscle myosin IIA heavy chain (Myh9) is strongly associated with adhesion structures of osteoclasts. In this study, we demonstrate that during osteoclastogenesis, myosin IIA heavy chain levels are temporarily suppressed, an event that stimulates the onset of cell fusion. This suppression is n...

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Bibliografische gegevens
Hoofdauteurs: McMichael, Brooke K., Wysolmerski, Robert B., Lee, Beth S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673295/
https://ncbi.nlm.nih.gov/pubmed/19269977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808621200
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