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Regulated Proteolysis of Nonmuscle Myosin IIA Stimulates Osteoclast Fusion
The nonmuscle myosin IIA heavy chain (Myh9) is strongly associated with adhesion structures of osteoclasts. In this study, we demonstrate that during osteoclastogenesis, myosin IIA heavy chain levels are temporarily suppressed, an event that stimulates the onset of cell fusion. This suppression is n...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673295/ https://ncbi.nlm.nih.gov/pubmed/19269977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808621200 |
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