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Structural and biochemical characterization of CRN-5 and Rrp46: An exosome component participating in apoptotic DNA degradation

Rrp46 was first identified as a protein component of the eukaryotic exosome, a protein complex involved in 3′ processing of RNA during RNA turnover and surveillance. The Rrp46 homolog, CRN-5, was subsequently characterized as a cell death-related nuclease, participating in DNA fragmentation during a...

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Hlavní autoři: Yang, Che-Chuan, Wang, Yi-Ting, Hsiao, Yu-Yuan, Doudeva, Lyudmila G., Kuo, Pan-Hsien, Chow, Sih Yao, Yuan, Hanna S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924534/
https://ncbi.nlm.nih.gov/pubmed/20660080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2180810
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