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Structural and biochemical characterization of CRN-5 and Rrp46: An exosome component participating in apoptotic DNA degradation
Rrp46 was first identified as a protein component of the eukaryotic exosome, a protein complex involved in 3′ processing of RNA during RNA turnover and surveillance. The Rrp46 homolog, CRN-5, was subsequently characterized as a cell death-related nuclease, participating in DNA fragmentation during a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924534/ https://ncbi.nlm.nih.gov/pubmed/20660080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2180810 |
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