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Structural and biochemical characterization of the yeast exosome component Rrp40

The exosome is a protein complex that is important in both degradation and 3′-processing of eukaryotic RNAs. We present the crystal structure of the Rrp40 exosome subunit from Saccharomyces cerevisiae at a resolution of 2.2 Å. The structure comprises an S1 domain and an unusual KH (K homology) domai...

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Detalhes bibliográficos
Main Authors: Oddone, Anna, Lorentzen, Esben, Basquin, Jerome, Gasch, Alexander, Rybin, Vladimir, Conti, Elena, Sattler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796750/
https://ncbi.nlm.nih.gov/pubmed/17159918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400856
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