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Crystal Structure of CRN-4: Implications for Domain Function in Apoptotic DNA Degradation

Cell death related nuclease 4 (CRN-4) is one of the apoptotic nucleases involved in DNA degradation in Caenorhabditis elegans. To understand how CRN-4 is involved in apoptotic DNA fragmentation, we analyzed CRN-4's biochemical properties, in vivo cell functions, and the crystal structures of CR...

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Autori principali: Hsiao, Yu-Yuan, Nakagawa, Akihisa, Shi, Zhonghao, Mitani, Shohei, Xue, Ding, Yuan, Hanna S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612515/
https://ncbi.nlm.nih.gov/pubmed/18981218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01006-08
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