Structural Insights into Apoptotic DNA Degradation by CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans

Endonuclease G (EndoG) is a mitochondrial protein that traverses to the nucleus and participates in chromosomal DNA degradation during apoptosis in yeast, worms, flies, and mammals. However, it remains unclear how EndoG binds and digests DNA. Here we show that the Caenorhabditis elegans CPS-6, a hom...

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Detalhes bibliográficos
Main Authors: Lin, Jason L. J., Nakagawa, Akihisa, Lin, Chia Liang, Hsiao, Yu-Yuan, Yang, Wei-Zen, Wang, Yi-Ting, Doudeva, Lyudmila G., Skeen-Gaar, Riley Robert, Xue, Ding, Yuan, Hanna S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293555/
https://ncbi.nlm.nih.gov/pubmed/22223640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.316075
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