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Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca(2+) increase and cell death in Caenorhabditis elegans
HBx is a multifunctional hepatitis B virus (HBV) protein that is crucial for HBV infection and pathogenesis and a contributing cause of hepatocyte carcinogenesis. However, the host targets and mechanisms of action of HBx are poorly characterized. We show here that expression of HBx in Caenorhabditis...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494929/ https://ncbi.nlm.nih.gov/pubmed/23091037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204652109 |
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