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Regulation of Prostate Cancer Cell Survival by Protein Kinase Cϵ Involves Bad Phosphorylation and Modulation of the TNFα/JNK Pathway

Protein kinase Cϵ (PKCϵ), a diacyglycerol- and phorbol ester-responsive serine-threonine kinase, has been implicated in mitogenic and survival control, and it is markedly overexpressed in human tumors, including in prostate cancer. Although prostate cancer cells undergo apoptosis in response to phor...

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Detalhes bibliográficos
Main Authors: Meshki, John, Caino, M. Cecilia, von Burstin, Vivian A., Griner, Erin, Kazanietz, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924002/
https://ncbi.nlm.nih.gov/pubmed/20566643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.128371
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