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Phosphorylation of Bad at Thr-201 by JNK1 Promotes Glycolysis through Activation of Phosphofructokinase-1

The mitogen-activated protein kinase JNK1 suppresses interleukin-3 withdrawal-induced cell death through phosphorylation of the BH3-only pro-apoptotic Bcl-2 family protein Bad at Thr-201. It is unknown whether JNK1 regulates glycolysis, an important metabolic process that is involved in cell surviva...

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Autors principals: Deng, Hongbin, Yu, Fei, Chen, Jianqun, Zhao, Yingming, Xiang, Jialing, Lin, Anning
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475697/
https://ncbi.nlm.nih.gov/pubmed/18469002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800024200
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