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Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy

Macroautophagy is a vacuolar lysosomal catabolic pathway that is stimulated during periods of nutrient starvation to preserve cell integrity. Ceramide is a bioactive sphingolipid associated with a large range of cell processes. Here we show that short-chain ceramides (C(2)-ceramide and C(6)-ceramide...

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Autori principali: Pattingre, Sophie, Bauvy, Chantal, Carpentier, Stéphane, Levade, Thierry, Levine, Beth, Codogno, Patrice
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631952/
https://ncbi.nlm.nih.gov/pubmed/19029119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805920200
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