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Ceramide-induced autophagy: To junk or to protect cells?

Ceramide is a sphingolipid bioactive molecule that induces apoptosis and other forms of cell death, and triggers macroautophagy (referred to below as autophagy). Like amino acid starvation, ceramide triggers autophagy by interfering with the mTOR-signaling pathway, and by dissociating the Beclin 1:B...

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Autors principals: Pattingre, Sophie, Bauvy, Chantal, Levade, Thierry, Levine, Beth, Codogno, Patrice
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501009/
https://ncbi.nlm.nih.gov/pubmed/19337026
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