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Autophagy modulation as a potential therapeutic target for diverse diseases
Autophagy is an essential, conserved lysosomal degradation pathway that controls the quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It begins when double-membraned autophagosomes engulf portions of the cytoplasm, which is followed by fusion of these vesicles with...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518431/ https://ncbi.nlm.nih.gov/pubmed/22935804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3802 |
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