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Therapeutic induction of autophagy to modulate neurodegenerative disease progression

There is accumulating evidence that aggregating, misfolded proteins may have an impact on autophagic function, suggesting that this could be a secondary pathological mechanism in many diseases. In this review, we focus on the role of autophagy in four major neurodegenerative diseases: Alzheimer dise...

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Autors principals: Hochfeld, Warren E, Lee, Shirley, Rubinsztein, David C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647215/
https://ncbi.nlm.nih.gov/pubmed/23377551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.189
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