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Regulation of Prostate Cancer Cell Survival by Protein Kinase Cϵ Involves Bad Phosphorylation and Modulation of the TNFα/JNK Pathway
Protein kinase Cϵ (PKCϵ), a diacyglycerol- and phorbol ester-responsive serine-threonine kinase, has been implicated in mitogenic and survival control, and it is markedly overexpressed in human tumors, including in prostate cancer. Although prostate cancer cells undergo apoptosis in response to phor...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924002/ https://ncbi.nlm.nih.gov/pubmed/20566643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.128371 |
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