A Novel Cross-talk in Diacylglycerol Signaling: THE RAC-GAP β2-CHIMAERIN IS NEGATIVELY REGULATED BY PROTEIN KINASE Cδ-MEDIATED PHOSPHORYLATION

Although the family of chimaerin Rac-GAPs has recently gained significant attention for their involvement in development, cancer, and neuritogenesis, little is known about their molecular regulation. Chimaerins are activated by the lipid second messenger diacylglycerol via their C1 domain upon activ...

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Detalhes bibliográficos
Main Authors: Griner, Erin M., Caino, M. Cecilia, Soledad Sosa, Maria, Colón-González, Francheska, Chalmers, Michael J., Mischak, Harald, Kazanietz, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878072/
https://ncbi.nlm.nih.gov/pubmed/20335173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.099036
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