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Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response
The integrated stress response (ISR) protects cells from numerous forms of stress and is involved in the growth of solid tumours; however, it is unclear how the ISR acts on cellular proliferation. We have developed a model of ISR signalling with which to study its effects on tissue growth. Overexpre...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Company of Biologists
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923568/ https://ncbi.nlm.nih.gov/pubmed/20682638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.070078 |
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