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Chk1 Is Required for Spindle Checkpoint Function
The spindle checkpoint delays anaphase onset in cells with mitotic spindle defects. Here, we show that Chk1, a component of the DNA damage and replication checkpoints, protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle funct...
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| Publicado no: | Dev Cell |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7115955/ https://ncbi.nlm.nih.gov/pubmed/17276342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.01.003 |
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