A Conserved Proliferating Cell Nuclear Antigen-interacting Protein Sequence in Chk1 Is Required for Checkpoint Function

Human checkpoint kinase 1 (Chk1) is an essential kinase required for cell cycle checkpoints and for coordination of DNA synthesis. To gain insight into the mechanisms by which Chk1 carries out these functions, we used mass spectrometry to identify previously uncharacterized interacting partners of C...

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Hlavní autoři: Scorah, Jennifer, Dong, Meng-Qiu, Yates, John R., Scott, Mary, Gillespie, David, McGowan, Clare H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427339/
https://ncbi.nlm.nih.gov/pubmed/18448427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800369200
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