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A Conserved Proliferating Cell Nuclear Antigen-interacting Protein Sequence in Chk1 Is Required for Checkpoint Function

Human checkpoint kinase 1 (Chk1) is an essential kinase required for cell cycle checkpoints and for coordination of DNA synthesis. To gain insight into the mechanisms by which Chk1 carries out these functions, we used mass spectrometry to identify previously uncharacterized interacting partners of C...

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書誌詳細
主要な著者: Scorah, Jennifer, Dong, Meng-Qiu, Yates, John R., Scott, Mary, Gillespie, David, McGowan, Clare H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427339/
https://ncbi.nlm.nih.gov/pubmed/18448427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800369200
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