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An ATM–Chk2–INCENP pathway activates the abscission checkpoint

During cell division, in response to chromatin bridges, the chromosomal passenger complex (CPC) delays abscission to prevent chromosome breakage or tetraploidization. Here, we show that inhibition of ATM or Chk2 kinases impairs CPC localization to the midbody center, accelerates midbody resolution i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Petsalaki, Eleni, Zachos, George
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769160/
https://ncbi.nlm.nih.gov/pubmed/33355621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202008029
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