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An ATM–Chk2–INCENP pathway activates the abscission checkpoint
During cell division, in response to chromatin bridges, the chromosomal passenger complex (CPC) delays abscission to prevent chromosome breakage or tetraploidization. Here, we show that inhibition of ATM or Chk2 kinases impairs CPC localization to the midbody center, accelerates midbody resolution i...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7769160/ https://ncbi.nlm.nih.gov/pubmed/33355621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202008029 |
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