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An ATM–Chk2–INCENP pathway activates the abscission checkpoint
During cell division, in response to chromatin bridges, the chromosomal passenger complex (CPC) delays abscission to prevent chromosome breakage or tetraploidization. Here, we show that inhibition of ATM or Chk2 kinases impairs CPC localization to the midbody center, accelerates midbody resolution i...
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| Gepubliceerd in: | J Cell Biol |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Rockefeller University Press
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7769160/ https://ncbi.nlm.nih.gov/pubmed/33355621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202008029 |
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