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Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching Between Two DNA Bound States
Human DNA ligase III has essential functions in nuclear and mitochondrial DNA replication and repair and contains a PARP-like zinc finger (ZnF) that increases DNA nick-joining and intermolecular DNA ligation. Yet, the bases for ligase III specificity and structural variation among human ligases are...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922849/ https://ncbi.nlm.nih.gov/pubmed/20518483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100503w |
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