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Eukaryotic DNA Ligases: Structural and Functional Insights

DNA ligases are required for DNA replication, repair, and recombination. In eukaryotes, there are three families of ATP-dependent DNA ligases. Members of the DNA ligase I and IV families are found in all eukaryotes, whereas DNA ligase III family members are restricted to vertebrates. These enzymes s...

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Detalhes bibliográficos
Main Authors: Ellenberger, Tom, Tomkinson, Alan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933818/
https://ncbi.nlm.nih.gov/pubmed/18518823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biochem.77.061306.123941
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