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Two DNA-binding and Nick Recognition Modules in Human DNA Ligase III
Human DNA ligase III contains an N-terminal zinc finger domain that binds to nicks and gaps in DNA. This small domain has been described as a DNA nick sensor, but it is not required for DNA nick joining activity in vitro. In light of new structural information for mammalian ligases, we measured the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447648/ https://ncbi.nlm.nih.gov/pubmed/18238776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708175200 |
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