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Two DNA-binding and Nick Recognition Modules in Human DNA Ligase III

Human DNA ligase III contains an N-terminal zinc finger domain that binds to nicks and gaps in DNA. This small domain has been described as a DNA nick sensor, but it is not required for DNA nick joining activity in vitro. In light of new structural information for mammalian ligases, we measured the...

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Hlavní autoři: Cotner-Gohara, Elizabeth, Kim, In-Kwon, Tomkinson, Alan E., Ellenberger, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447648/
https://ncbi.nlm.nih.gov/pubmed/18238776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708175200
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