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Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching Between Two DNA Bound States

Human DNA ligase III has essential functions in nuclear and mitochondrial DNA replication and repair and contains a PARP-like zinc finger (ZnF) that increases DNA nick-joining and intermolecular DNA ligation. Yet, the bases for ligase III specificity and structural variation among human ligases are...

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Bibliografiska uppgifter
Huvudupphovsmän: Cotner-Gohara, Elizabeth, Kim, In-Kwon, Hammel, Michal, Tainer, John A., Tomkinson, Alan E., Ellenberger, Tom
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922849/
https://ncbi.nlm.nih.gov/pubmed/20518483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100503w
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