Nalaganje...
Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic
The pharmacologic utility of lengthy peptides can be hindered by loss of bioactive structure and rapid proteolysis, which limits bioavailability. For example, enfuvirtide (Fuzeon, T20, DP178), a 36-amino acid peptide that inhibits human immunodeficiency virus type 1 (HIV-1) infection by effectively...
Shranjeno v:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2010
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922607/ https://ncbi.nlm.nih.gov/pubmed/20660316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002713107 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|