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fAUC/MIC is the most predictive pharmacokinetic/pharmacodynamic index of colistin against Acinetobacter baumannii in murine thigh and lung infection models

OBJECTIVES: To elucidate the pharmacokinetic/pharmacodynamic (PK/PD) index that predicts colistin efficacy against Acinetobacter baumannii in neutropenic murine thigh and lung infection models, and to determine the extent of the emergence of resistance in vivo to colistin. METHODS: PK/PD of colistin...

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Detaylı Bibliyografya
Asıl Yazarlar: Dudhani, Rajesh V., Turnidge, John D., Nation, Roger L., Li, Jian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920176/
https://ncbi.nlm.nih.gov/pubmed/20573659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq226
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