The transcriptomic response of Acinetobacter baumannii to colistin and doripenem alone and in combination in an in vitro pharmacokinetics/pharmacodynamics model

OBJECTIVES: Colistin remains a last-line treatment for MDR Acinetobacter baumannii and combined use of colistin and carbapenems has shown synergistic effects against MDR strains. In order to understand the bacterial responses to these antibiotics, we analysed the transcriptome of A. baumannii follow...

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Bibliographic Details
Published in:J Antimicrob Chemother
Main Authors: Henry, Rebekah, Crane, Bethany, Powell, David, Deveson Lucas, Deanna, Li, Zhifeng, Aranda, Jesús, Harrison, Paul, Nation, Roger L., Adler, Ben, Harper, Marina, Boyce, John D., Li, Jian
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398468/
https://ncbi.nlm.nih.gov/pubmed/25587995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku536
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