The transcriptomic response of Acinetobacter baumannii to colistin and doripenem alone and in combination in an in vitro pharmacokinetics/pharmacodynamics model

OBJECTIVES: Colistin remains a last-line treatment for MDR Acinetobacter baumannii and combined use of colistin and carbapenems has shown synergistic effects against MDR strains. In order to understand the bacterial responses to these antibiotics, we analysed the transcriptome of A. baumannii follow...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Antimicrob Chemother
Prif Awduron: Henry, Rebekah, Crane, Bethany, Powell, David, Deveson Lucas, Deanna, Li, Zhifeng, Aranda, Jesús, Harrison, Paul, Nation, Roger L., Adler, Ben, Harper, Marina, Boyce, John D., Li, Jian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398468/
https://ncbi.nlm.nih.gov/pubmed/25587995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku536
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