Emergence of High-Level Colistin Resistance in an Acinetobacter baumannii Clinical Isolate Mediated by Inactivation of the Global Regulator H-NS

Colistin is a crucial last-line drug used for the treatment of life-threatening infections caused by multidrug-resistant strains of the Gram-negative bacterium Acinetobacter baumannii. However, colistin-resistant A. baumannii isolates can still be isolated following failed colistin therapy. Resistan...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Deveson Lucas, Deanna, Crane, Bethany, Wright, Amy, Han, Mei-Ling, Moffatt, Jennifer, Bulach, Dieter, Gladman, Simon L., Powell, David, Aranda, Jesus, Seemann, Torsten, Machado, Diana, Pacheco, Teresa, Marques, Teresa, Viveiros, Miguel, Nation, Roger, Li, Jian, Harper, Marina, Boyce, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021671/
https://ncbi.nlm.nih.gov/pubmed/29712662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02442-17
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