Insertion Sequence ISAba11 Is Involved in Colistin Resistance and Loss of Lipopolysaccharide in Acinetobacter baumannii

Infections caused by Acinetobacter baumannii are of increasing concern, largely due to the multidrug resistance of many strains. Here we show that insertion sequence ISAba11 movement can result in inactivation of the A. baumannii lipid A biosynthesis genes lpxA and lpxC, resulting in the complete lo...

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Bibliografiset tiedot
Päätekijät: Moffatt, Jennifer H., Harper, Marina, Adler, Ben, Nation, Roger L., Li, Jian, Boyce, John D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2011
Aiheet:
Mechanisms of Resistance
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101452/
https://ncbi.nlm.nih.gov/pubmed/21402838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01732-10
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