Synergistic Activity of Colistin and Rifampin Combination against Multidrug-Resistant Acinetobacter baumannii in an In Vitro Pharmacokinetic/Pharmacodynamic Model

Combination therapy may be required for multidrug-resistant (MDR) Acinetobacter baumannii. This study systematically investigated bacterial killing and emergence of colistin resistance with colistin and rifampin combinations against MDR A. baumannii. Studies were conducted over 72 h in an in vitro p...

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Detalhes bibliográficos
Main Authors: Lee, Hee Ji, Bergen, Phillip J., Bulitta, Jurgen B., Tsuji, Brian, Forrest, Alan, Nation, Roger L., Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719722/
https://ncbi.nlm.nih.gov/pubmed/23716052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00703-13
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