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Resistance to Integrase Inhibitors

Integrase (IN) is a clinically validated target for the treatment of human immunodeficiency virus infections and raltegravir exhibits remarkable clinical activity. The next most advanced IN inhibitor is elvitegravir. However, mutant viruses lead to treatment failure and mutations within the IN codin...

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Bibliografische gegevens
Hoofdauteurs: Métifiot, Mathieu, Marchand, Christophe, Maddali, Kasthuraiah, Pommier, Yves
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Molecular Diversity Preservation International (MDPI) 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920056/
https://ncbi.nlm.nih.gov/pubmed/20706558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2071347
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