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HIV-1 IN Inhibitors: 2010 Update and Perspectives

Integrase (IN) is the newest validated target against AIDS and retroviral infections. The remarkable activity of raltegravir (Isentress(®)) led to its rapid approval by the FDA in 2007 as the first IN inhibitor. Several other IN strand transfer inhibitors (STIs) are in development with the primary g...

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Hlavní autoři: Marchand, Christophe, Maddali, Kasthuraiah, Metifiot, Mathieu, Pommier, Yves
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860603/
https://ncbi.nlm.nih.gov/pubmed/19747122
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