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A membrane capture assay for lipid kinase activity
Phosphoinositide kinases such as PI3-kinase synthesize lipid second messengers that control diverse cellular processes. Recently, these enzymes have emerged as an important class of drug targets, and there is significant interest in discovering new lipid kinase inhibitors. We describe here a procedu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919233/ https://ncbi.nlm.nih.gov/pubmed/17947987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2007.361 |
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