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A membrane capture assay for lipid kinase activity

Phosphoinositide kinases such as PI3-kinase synthesize lipid second messengers that control diverse cellular processes. Recently, these enzymes have emerged as an important class of drug targets, and there is significant interest in discovering new lipid kinase inhibitors. We describe here a procedu...

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Bibliografiska uppgifter
Huvudupphovsmän: Knight, Zachary A, Feldman, Morri E, Balla, Andras, Balla, Tamas, Shokat, Kevan M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919233/
https://ncbi.nlm.nih.gov/pubmed/17947987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2007.361
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