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Multistep Compositional Remodeling of Supported Lipid Membranes by Interfacially Active Phosphatidylinositol Kinases

The multienzyme catalytic phosphorylation of phosphatidylinositol (PI) in a supported lipid membrane platform is demonstrated for the first time. One-step treatment with PI 4-kinase IIIβ (PI4Kβ) yielded PI 4-phosphate (PI4P), while a multistep enzymatic cascade of PI4Kβ followed by PIP 5-kinase prod...

詳細記述

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書誌詳細
出版年:Anal Chem
主要な著者: Tabaei, Seyed R., Guo, Feng, Rutaganira, Florentine U., Vafaei, Setareh, Choong, Ingrid, Shokat, Kevan M., Glenn, Jeffrey S., Cho, Nam-Joon
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291064/
https://ncbi.nlm.nih.gov/pubmed/27118725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b01293
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