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Endosomal Phosphatidylinositol 3-Kinase Is Essential for Canonical GPCR Signaling
G protein–coupled receptors (GPCRs), the largest family of signaling receptors, are critically regulated by endosomal trafficking, suggesting that endosomes might provide new strategies for manipulating GPCR signaling. Here we test this hypothesis by focusing on class III phosphatidylinositol 3-kina...
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| Publicado no: | Mol Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5198513/ https://ncbi.nlm.nih.gov/pubmed/27821547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.106252 |
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