Lineage-specific T-cell reconstitution following in vivo CD4(+) and CD8(+) lymphocyte depletion in nonhuman primates

Many features of T-cell homeostasis in primates are still unclear, thus limiting our understanding of AIDS pathogenesis, in which T-cell homeostasis is lost. Here, we performed experiments of in vivo CD4(+) or CD8(+) lymphocyte depletion in 2 nonhuman primate species, rhesus macaques (RMs) and sooty...

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Main Authors: Engram, Jessica C., Cervasi, Barbara, Borghans, Jose A. M., Klatt, Nichole R., Gordon, Shari N., Chahroudi, Ann, Else, James G., Mittler, Robert S., Sodora, Donald L., de Boer, Rob J., Brenchley, Jason M., Silvestri, Guido, Paiardini, Mirko
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Immunobiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918331/
https://ncbi.nlm.nih.gov/pubmed/20484087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-263814
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