Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

Acute HIV infection is characterized by massive loss of CD4 T cells from the gastrointestinal (GI) tract. Th17 cells are critical in the defense against microbes, particularly at mucosal surfaces. Here we analyzed Th17 cells in the blood, GI tract, and broncheoalveolar lavage of HIV-infected and uni...

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Detalhes bibliográficos
Main Authors: Brenchley, Jason M., Paiardini, Mirko, Knox, Kenneth S., Asher, Ava I., Cervasi, Barbara, Asher, Tedi E., Scheinberg, Phillip, Price, David A., Hage, Chadi A., Kholi, Lisa M., Khoruts, Alexander, Frank, Ian, Else, James, Schacker, Timothy, Silvestri, Guido, Douek, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556618/
https://ncbi.nlm.nih.gov/pubmed/18664624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-159301
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