Lineage-specific T-cell reconstitution following in vivo CD4(+) and CD8(+) lymphocyte depletion in nonhuman primates

Many features of T-cell homeostasis in primates are still unclear, thus limiting our understanding of AIDS pathogenesis, in which T-cell homeostasis is lost. Here, we performed experiments of in vivo CD4(+) or CD8(+) lymphocyte depletion in 2 nonhuman primate species, rhesus macaques (RMs) and sooty...

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Detalhes bibliográficos
Main Authors: Engram, Jessica C., Cervasi, Barbara, Borghans, Jose A. M., Klatt, Nichole R., Gordon, Shari N., Chahroudi, Ann, Else, James G., Mittler, Robert S., Sodora, Donald L., de Boer, Rob J., Brenchley, Jason M., Silvestri, Guido, Paiardini, Mirko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918331/
https://ncbi.nlm.nih.gov/pubmed/20484087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-263814
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