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Computational Mutation Scanning and Drug Resistance Mechanisms of HIV-1 Protease Inhibitors

The drug resistance of various clinically available HIV-1 protease inhibitors has been studied using a new computational protocol, i.e. computational mutation scanning (CMS), leading to valuable insights into the resistance mechanisms and structure-resistance correction of the HIV-1 protease inhibit...

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Hlavní autoři: Hao, Ge-Fei, Yang, Guang-Fu, Zhan, Chang-Guo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916083/
https://ncbi.nlm.nih.gov/pubmed/20604558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp102546s
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