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Computational Mutation Scanning and Drug Resistance Mechanisms of HIV-1 Protease Inhibitors
The drug resistance of various clinically available HIV-1 protease inhibitors has been studied using a new computational protocol, i.e. computational mutation scanning (CMS), leading to valuable insights into the resistance mechanisms and structure-resistance correction of the HIV-1 protease inhibit...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916083/ https://ncbi.nlm.nih.gov/pubmed/20604558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp102546s |
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