HIV-1 Protease Mutations and Protease Inhibitor Cross-Resistance

The effects of many protease inhibitor (PI)-selected mutations on the susceptibility to individual PIs are unknown. We analyzed in vitro susceptibility test results on 2,725 HIV-1 protease isolates. More than 2,400 isolates had been tested for susceptibility to fosamprenavir, indinavir, nelfinavir,...

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Detalhes bibliográficos
Main Authors: Rhee, Soo-Yon, Taylor, Jonathan, Fessel, W. Jeffrey, Kaufman, David, Towner, William, Troia, Paolo, Ruane, Peter, Hellinger, James, Shirvani, Vivian, Zolopa, Andrew, Shafer, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944562/
https://ncbi.nlm.nih.gov/pubmed/20660676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00574-10
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