Mutation Patterns and Structural Correlates in Human Immunodeficiency Virus Type 1 Protease following Different Protease Inhibitor Treatments

Although many human immunodeficiency virus type 1 (HIV-1)-infected persons are treated with multiple protease inhibitors in combination or in succession, mutation patterns of protease isolates from these persons have not been characterized. We collected and analyzed 2,244 subtype B HIV-1 isolates fr...

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Detalhes bibliográficos
Main Authors: Wu, Thomas D., Schiffer, Celia A., Gonzales, Matthew J., Taylor, Jonathan, Kantor, Rami, Chou, Sunwen, Israelski, Dennis, Zolopa, Andrew R., Fessel, W. Jeffrey, Shafer, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152121/
https://ncbi.nlm.nih.gov/pubmed/12663790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4836-4847.2003
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