Identification of Genotypic Changes in Human Immunodeficiency Virus Protease That Correlate with Reduced Susceptibility to the Protease Inhibitor Lopinavir among Viral Isolates from Protease Inhibitor-Experienced Patients

The association of genotypic changes in human immunodeficiency virus (HIV) protease with reduced in vitro susceptibility to the new protease inhibitor lopinavir (previously ABT-378) was explored using a panel of viral isolates from subjects failing therapy with other protease inhibitors. Two statist...

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Autori principali: Kempf, Dale J., Isaacson, Jeffrey D., King, Martin S., Brun, Scott C., Xu, Yi, Real, Kathryn, Bernstein, Barry M., Japour, Anthony J., Sun, Eugene, Rode, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC114981/
https://ncbi.nlm.nih.gov/pubmed/11462018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7462-7469.2001
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