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Munc13 C(2)B-Domain – an Activity-Dependent Ca(2+)-Regulator of Synaptic Exocytosis
Munc13 is a multidomain protein of presynaptic active zones that mediates the priming and plasticity of synaptic vesicle exocytosis, but the mechanisms involved remain unclear. Here, we use biophysical, biochemical, and electrophysiological approaches to demonstrate that the central C(2)B-domain of...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916016/ https://ncbi.nlm.nih.gov/pubmed/20154707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1758 |
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